EC Number   |
Protein Variants |
Reference |
|---|
  5.5.1.16 | A234N/F235V |
the mutant predominantly produces tuberculosinyl diphosphate, with trace amounts of labda-8,13-dienyl diphosphate and labda-7,13-dienyl diphosphate from geranylgeranyl diphosphate |
768146 |
| 5.5.1.16 | D295A |
almost completely inactive |
-, 768146 |
| 5.5.1.16 | F171A |
the mutant forms small amounts of tuberculosinyl diphosphate and labda-8,13-dienyl diphosphate, along with trace amounts of labda-7,13-dienyl diphosphate from geranylgeranyl diphosphate |
768146 |
| 5.5.1.16 | F171H |
the mutant generates significant amounts of copalyl diphosphate from geranylgeranyl diphosphate |
-, 768146 |
| 5.5.1.16 | F171H/A234N/F235V |
the mutations lead to an almost complete loss of metabolic flux |
768146 |
| 5.5.1.16 | Y328F |
the mutant generates an alternative product (labda-7,13-dienyl diphosphate) from geranylgeranyl diphosphate |
-, 768146 |
| 5.5.1.16 | Y328F/Y479F |
the mutant generates an alternative product (labda-7,13-dienyl diphosphate) from geranylgeranyl diphosphate |
-, 768146 |
| 5.5.1.16 | Y479F |
the mutant generates an alternative product (labda-7,13-dienyl diphosphate) from geranylgeranyl diphosphate |
-, 768146 |
