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Results 1 - 5 of 5
EC Number
Amino acid exchange
Commentary
Reference
D218V
natural mutation
K192A
mutation decreases in vitro epimerase activity by more than 95% but does not affect dehydratase activity, reaction of EC 4.2.1.136. Mutant cells have essentially normal NAD(P)HX dehydratase activity and NAD(P)HX levels. Cells show metabolome changes, particularly in amino acids, which exceed those in cells lacking the entire yjeF gene. Mutant cells also have reduced levels of free (i.e. weakly bound or unbound) pyridoxal 5'-phosphate
Lys270del
natural mutation
Q66Stop
natural mutation
Tyr59Stop
natural mutation
Results 1 - 5 of 5