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EC Number
Amino acid exchange
enzyme is inactive
variant with altered cleavage recognition site
induction of RNAi against brucipain of Trypanosoma brucei does not cure mice from infection, however, 50% of these mice survive 60 days longer than uninduced controls. The ability of Trypanosoma brucei to cross an in vitro model of the human blood-brain barrier is also reduced by brucipain RNAi induction
Results 1 - 3 of 3