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Results 1 - 3 of 3
EC Number
Amino acid exchange
Commentary
Reference
C25A
enzyme is inactive
E219P
variant with altered cleavage recognition site
more
induction of RNAi against brucipain of Trypanosoma brucei does not cure mice from infection, however, 50% of these mice survive 60 days longer than uninduced controls. The ability of Trypanosoma brucei to cross an in vitro model of the human blood-brain barrier is also reduced by brucipain RNAi induction
Results 1 - 3 of 3