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Results 1 - 10 of 31 > >>
EC Number
Amino acid exchange
Commentary
Reference
D715A
factor B mutation, severly reduces hemolytic activity, in complex with C3b no cleavage of C3
D715E
factor B mutation, severly reduces hemolytic activity, in complex with C3b no cleavage of C3
D715N
factor B mutation, severly reduces hemolytic activity, in complex with C3b no cleavage of C3
D715S
factor B mutation, severly reduces hemolytic activity
D715Y
factor B mutation, severly reduces hemolytic activity
F716A
factor B mutation, severly reduces hemolytic activity
D254G
mutation in the Bb component decreases sensitivity to DAF to 9% of the wild-type value, sensitivity to CR1 to 4% of the wild-type value and sensitivity to Factor H to 48% of the wild-type value
D382A
mutation in the Bb component decreases sensitivity to DAF to 36% of the wild-type value, sensitivity to CR1 to 41% of the wild-type value
D382N
mutation in the Bb component decreases sensitivity to DAF to 54% of the wild-type value
D445A
mutation in the Bb component decreases sensitivity to CR1 to 71% of the wild-type value
Results 1 - 10 of 31 > >>