EC Number   |
Protein Variants |
Reference  |
|---|
   3.4.17.23 | more |
construction of a soluble truncated mutant enzyme lacking the transmembrane and cytosolic domains |
657967, 659147 |
| 3.4.17.23 | H345A |
no activity with (7-methoxycoumarin-4-yl)acetyl-APK-2,4-dinitrophenyl |
668550 |
| 3.4.17.23 | H345L |
no activity with (7-methoxycoumarin-4-yl)acetyl-APK-2,4-dinitrophenyl |
668550 |
| 3.4.17.23 | H505A |
1.5% of wild-type activity with (7-methoxycoumarin-4-yl)acetyl-APK-2,4-dinitrophenyl as substrate |
668550 |
| 3.4.17.23 | H505L |
no activity with (7-methoxycoumarin-4-yl)acetyl-APK-2,4-dinitrophenyl |
668550 |
| 3.4.17.23 | R169Q |
as active as wild-type enzyme with (7-methoxycoumarin-4-yl)acetyl-APK-2,4-dinitrophenyl as substrate |
668550 |
| 3.4.17.23 | R273K |
no activity with (7-methoxycoumarin-4-yl)acetyl-APK-2,4-dinitrophenyl |
668550 |
| 3.4.17.23 | R273Q |
no activity with (7-methoxycoumarin-4-yl)acetyl-APK-2,4-dinitrophenyl |
668550 |
| 3.4.17.23 | R514Q |
about 10% of wild-type activity with (7-methoxycoumarin-4-yl)acetyl-APK-2,4-dinitrophenyl as substrate |
668550 |
| 3.4.17.23 | K481Q |
angiotensin I cleavage activity is 21% of wild-type activity, angiotensin II cleavage activity is 71.8% of wild-type activity |
692319 |
