EC Number   |
Protein Variants |
Reference |
|---|
   3.1.4.59 | D130A/H131A |
mutant fails to hydrolyze c-di-AMP |
-, 751993 |
| 3.1.4.59 | D134a/H135A/H136A |
mutation in DHH domain, complete loss of catalytic activity |
-, 750844 |
| 3.1.4.59 | D420A |
mutant exhibits residual activity against c-di-AMP, c-di-GMP, bis-p-nitrophenol phosphate, and thymidine monophosphate p-nitrophenol ester |
-, 751027 |
| 3.1.4.59 | D420A/D499A |
mutation totally abolishes the catalytic activity |
-, 751027 |
| 3.1.4.59 | G266D |
natural mutation identified in a strain displaying tolerance to inhibitors of peptidoglycan biosynthesis |
-, 749591 |
| 3.1.4.59 | G313A/G314A/G315A/H316A |
mutation in DHHA1 domain, mutasnt displays residual activity |
-, 750844 |
| 3.1.4.59 | T260K |
natural mutation identified in a strain displaying tolerance to inhibitors of peptidoglycan biosynthesis |
-, 749591 |
