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Results 1 - 10 of 23 > >>
EC Number
Amino acid exchange
Commentary
Reference
C199A
the mutant shows about 90.4% of wild type activity
D122A
the mutant shows about 24.5% of wild type activity
D160A
the mutant shows about 57% of wild type activity
D167A
the mutant shows about 68.7% of wild type activity
D184A
the mutant shows about 39.3% of wild type activity
D35A
the mutant shows strongly reduced activity compared to the wild type enzyme
D77N/D78N
hydrolysis of O-acetyl-D-ADP-ribose is abolished by these mutations
E238Q/E239Q
the mutant shows wild type hydrolytic activity with O-acetyl-D-ADP-ribose
E261Q/E262Q
the mutant shows wild type hydrolytic activity with O-acetyl-D-ADP-ribose
G100E
the mutant isoform MacroD2 lacks hydrolase and ADP-ribose-binding activities
Results 1 - 10 of 23 > >>