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Results 1 - 7 of 7
EC Number
Protein Variants
Commentary
Reference
D143
residue is the base responsible for proton abstraction from the pantoate hydroxy group
E134A
residue is involved in binding with Mg2+
H131A
residue is involved in pantoate recognition. 77% of wild-type activity in presence of 6 mM pantoate and 4 mM ATP
R155A
residue is involved in pantoate recognition and plays an important role in catalysis
S104A
residue is involved in binding with phosphate
S28A
residue is involved in pantoate recognition. 3.7% of wild-type activity in presence of 6 mM pantoate and 4 mM ATP
T186A
residue is involved in pantoate recognition and plays an important role in catalysis. Thr186 is involved in dimer assambly
Results 1 - 7 of 7