Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Protein Variants

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 11 > >>
EC Number Protein Variants Commentary Reference
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18R414K 19.9% of wild-type activity with substrate beta-alanine, 9.6% with substrate cadaverine, 20.5% with substrate 1,3-diaminopropane -, 737507
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18D392K site-directed mutagenesis, slightly reduced activity compared to wild-type enzyme 759057
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18E345F site-directed mutagenesis, reduced activity compared to wild-type enzyme 759057
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18E391K site-directed mutagenesis, reduced activity compared to wild-type enzyme 759057
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18G165M best DELTADELTAG prediction, the mutant shows a 3.3fold reduction in enzymatic activity and an only a slight improvement in the Tm value, which stresses the importance of experimental evaluation of the theoretical data 759057
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18G165M site-directed mutagenesis, reduced activity compared to wild-type enzyme 759057
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18G98M site-directed mutagenesis, slightly reduced activity compared to wild-type enzyme 759057
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18G98M/D392K site-directed mutagenesis, reduced activity compared to wild-type enzyme 759057
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18G98M/E345F site-directed mutagenesis, reduced activity compared to wild-type enzyme 759057
Show all pathways known for 2.6.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.18more synthesis and optical resolution of beta-phenylalanine and other important aromatic beta-amino acids by biotransformation utilizing an omega-transaminase (omega-TA) from Variovorax paradoxus. Design of mutant variants of the omega-TA to gain higher process stability on the basis of predictions calculated by using the FoldX software. Thermostabilization of a nonthermostable S-selective omega-TA by FoldX-guided site-directed mutagenesis. The melting point (Tm) of the best-performing mutant is increased to 59.3°C, an increase of 4.0°C relative to the Tm value of the wild-type enzyme, whereby the mutant fully retains its specific activity 759057
Results 1 - 10 of 11 > >>