EC Number   |
Protein Variants  |
Reference |
|---|
    2.3.1.12 | A174S |
mutation in the inner lipoyl-bearing domain (L2), pyruvate dehydrogenase kinase 2 binding: 69% |
672273 |
| 2.3.1.12 | D164A |
mutation in the inner lipoyl-bearing domain (L2), pyruvate dehydrogenase kinase 2 binding: 55% |
672273 |
| 2.3.1.12 | D172A |
mutation in the inner lipoyl-bearing domain (L2), pyruvate dehydrogenase kinase 2 binding: 66% |
672273 |
| 2.3.1.12 | E162A |
mutation in the inner lipoyl-bearing domain (L2), pyruvate dehydrogenase kinase 2 binding: 93% |
672273 |
| 2.3.1.12 | E179A |
mutation in the inner lipoyl-bearing domain (L2), pyruvate dehydrogenase kinase 2 binding: 28% |
672273 |
| 2.3.1.12 | E182A |
binding of mutant L2 domain to pyruvate dehydrogenase phosphatase isozyme 1 is hindered |
663011 |
| 2.3.1.12 | E182A |
mutation in the inner lipoyl-bearing domain (L2), pyruvate dehydrogenase kinase 2 binding: 100% |
672273 |
| 2.3.1.12 | E182Q |
binding of mutant L2 domain to pyruvate dehydrogenase phosphatase isozyme 1 is hindered |
663011 |
| 2.3.1.12 | E183A |
mutation in the inner lipoyl-bearing domain (L2), pyruvate dehydrogenase kinase 2 binding: 98% |
672273 |
| 2.3.1.12 | F231A |
ability to be post-translationally lipoylated remains |
486229 |
