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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170more a rsmG null mutant is streptomycin-resistant 721042
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170N39A inactive 733472
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170more mutations within the gene gidB confer low-level streptomycin resistance. gidB mutations emerge spontaneously at a high frequency of 0.000001 and, once emerged, result in vigorous emergence of high-level streptomycin-resistant mutants at a frequency more than 2000 times greater than that seen in wild-type strains -, 705767
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170C172S/A14C site-directed mutagenesis -, 779252
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170H53A site-directed mutagenesis of the catalytic residue, the mutant is partly streptomycin-resistant and shows reduced activity compared to the wild-type enzyme 721042
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170R139K site-directed mutagenesis of the catalytic residue, the mutant is partly streptomycin-resistant and shows reduced activity compared to the wild-type enzyme 721042
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170R139A site-directed mutagenesis of the catalytic residue, the mutant is streptomycin-resistant and catalytically inactive 721042
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170D56A site-directed mutagenesis of the catalytic residue, the mutant is streptomycin-resistant and shows reduced activity compared to the wild-type enzyme 721042
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170R197A site-directed mutagenesis of the RNA binding residue, the mutant is streptomycin-resistant and shows reduced activity compared to the wild-type enzyme 721042
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.170K165A site-directed mutagenesis of the RNA binding residue, the mutant is streptomycin-sensitive, but shows reduced activity compared to the wild-type enzyme 721042
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