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Results 1 - 10 of 31 > >>
EC Number Protein Variants Commentary Reference
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1S175A - 390913
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1R265A 2fold increase in KM-value of CoQD, 15% increase in KM-value of L-dihydroorotate 656285
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1H185A 4fold increase in KM-value of CoQD, 50% increase in KM-value of L-dihydroorotate 656285
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1L71F/C130S/V133T addition of the two residues comprising the conserved proton-transfer network of Class 2 dihydroorotate dehydrogenase from Escherichia coli to the C130S Class 1A enzyme of Lactococcus lacits. Mutation does not did not restore the function of the active site base or rapid flavin reduction. Kd for dihydroorotate is about three times tighter than the wild-type 724305
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1E206/K296E conversion of intermolecular salt bridge, mutant is fully active in concentrated solutions and dissociates into monomers upon dilution like wild-type enzyme 657291
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1K213E decrease in activity against dichlorophenolindophenol 656148
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1P131A decrease in activtiy against fumarate 656148
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1S129A decrease in activtiy against fumarate 656148
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1more deletions of N-terminal residues from 2 down to 40 result in generally unstable proteins with apo protein quickly precipitating and FMN remaining in solution. A truncated protein lacking residues 2 to 30 is sufficiently stable, has near to wild-type activity using molecular oxygen and 20fold lower activity using 2,6-dichlorophenolindophenol as electron acceptor 657355
Show all pathways known for 1.3.98.1Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.1more DHOD-knockout Trypanosoma cruzi do not express the enzyme protein and can not survive even in the presence of pyrimidine nucleosides, suggesting a vital role of fumarate reductase activity in the regulation of cellular redox balance 675478
Results 1 - 10 of 31 > >>