EC Number   |
Protein Variants |
Reference  |
|---|
   1.20.1.1 | A176R |
strongly decreased Km for NADP+ |
657956 |
| 1.20.1.1 | E175A |
strongly decreased Km for NADP+ |
657956 |
| 1.20.1.1 | E175A/A176R |
double mutant, 3.6-fold higher efficiency with NAD+, 1000-fold higher efficiency with NADP+, 3-fold favor for NADP+ over NAD+ as cofactor |
-, 657956, 658259 |
| 1.20.1.1 | E266Q |
significant increase in Km for both substrates, increase in turnover |
-, 658120 |
| 1.20.1.1 | H292F |
almost complete loss of activity |
658120 |
| 1.20.1.1 | H292K |
almost complete loss of activity |
658120 |
| 1.20.1.1 | H292N |
almost complete loss of activity |
-, 658120 |
| 1.20.1.1 | K76A |
significant increase in Km for both substrates |
-, 658120 |
| 1.20.1.1 | K76C |
significant increase in Km for both substrates |
658120 |
| 1.20.1.1 | K76M |
significant increase in Km for both substrates |
-, 658120 |
