EC Number   |
Protein Variants |
Reference  |
|---|
   1.1.1.346 | F22Y |
the mutation causes a 2.5fold decrease in Km for 2,5-didehydro-D-gluconate whereas the value of kcat remains essentially unchanged |
440307 |
| 1.1.1.346 | Q192R |
the mutation primarily affects the kcat parameter toward the 2,5-didehydro-D-gluconate substrate, increasing its value approximately 2.5fold, whereas Km is relatively unaffected, or increases slightly |
440307 |
| 1.1.1.346 | K233G |
the mutant shows decreased NADPH activity and increased NADH activity compared to the wild type enzyme |
440310 |
| 1.1.1.346 | K233H |
the mutant shows decreased NADPH activity compared to the wild type enzyme and no NADH activity |
440310 |
| 1.1.1.346 | K233M |
the mutant shows decreased NADPH activity and increased NADH activity compared to the wild type enzyme |
440310 |
| 1.1.1.346 | K233Q |
the mutant shows wild type NADPH activity and increased NADH activity |
440310 |
| 1.1.1.346 | K233R |
the mutant shows decreased NADPH activity compared to the wild type enzyme and no NADH activity |
440310 |
| 1.1.1.346 | K233S |
the mutant shows wild type NADPH activity and increased NADH activity compared to the wild type enzyme |
440310 |
| 1.1.1.346 | K233T |
the mutant shows wild type NADPH activity and no NADH activity |
440310 |
| 1.1.1.346 | R235C |
the mutant shows wild type NADPH activity and no NADH activity |
440310 |
