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Results 1 - 10 of 51 > >>
EC Number Protein Variants Commentary Reference
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346F22Y the mutation causes a 2.5fold decrease in Km for 2,5-didehydro-D-gluconate whereas the value of kcat remains essentially unchanged 440307
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346F22Y/A272G substrate-binding pocket double mutant with decreased kcat value for NADPH compared to the wild type enzyme 440311
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346F22Y/K232G/R235G/R238H/A272G mutant with wild type kcat value for NADPH 440311
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346F22Y/K232G/R235T/R238H/A272G 420 mutant with decreased kcat value for NADPH compared to the wild type enzyme 440311
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346F22Y/K232G/R238H/A272G mutant with decreased kcat value for NADPH compared to the wild type enzyme 440311
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346F22Y/K232G/R238H/A272G the mutant exhibits activity with NADH that is more than 2 orders of magnitude higher than that of the wild type enzyme and retains a high level of activity with NADPH 440311
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346F22Y/K232G/R238H/A272G the mutation enhances binding to NADH, while retaining to a large extent the ability to bind NADPH. The mutant is also more stable and can, therefore, be expected to exhibit greater effective activity at elevated temperatures in comparison to the wild type enzyme 657308
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346K232G/R238H mutant with decreased kcat value for NADPH compared to the wild type enzyme 440311
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346K233G the mutant shows decreased NADPH activity and increased NADH activity compared to the wild type enzyme 440310
Show all pathways known for 1.1.1.346Display the reaction diagram Show all sequences 1.1.1.346K233H the mutant shows decreased NADPH activity compared to the wild type enzyme and no NADH activity 440310
Results 1 - 10 of 51 > >>