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EC Number
Protein Variants
Commentary
Reference
1.1.1.248
L266A
decrease in kcat
698937
1.1.1.248
M271A
decrease in kcat
698937
1.1.1.248
F104A
increase in kcat
698937
1.1.1.248
M271A
increase in Km
698937
1.1.1.248
D107A
increase in Km, 2fold decrease in kcat
698937
1.1.1.248
L185A
increase in Km, decrease in kcat
698937
1.1.1.248
N272A
increase in Km, decrease in kcat
698937
1.1.1.248
I275A
increase in Km, shows an increase of velocity by a factor of 2.3
698937
1.1.1.248
T182A
moderate effects on substrate affinity
698937
1.1.1.248
K186V
moderate effects on substrate affinity, exhibits a turnover number similar to that of the wild-type
698937
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