EC Number   |
Protein Variants |
Reference |
|---|
    5.1.3.14 | DELTA1-234 |
mutant enzyme shows no N-epimerase activity |
660988 |
| 5.1.3.14 | DELTA1-356 |
mutant enzyme shows no N-epimerase activity |
660988 |
| 5.1.3.14 | DELTA1-39 |
mutant enzyme shows no N-epimerase activity |
660988 |
| 5.1.3.14 | DELTA383-722 |
epimerase activity is 2% of wild-type enzyme |
660988 |
| 5.1.3.14 | DELTA490-722 |
epimerase activity is 15% of wild-type enzyme |
660988 |
| 5.1.3.14 | DELTA597-722 |
epimerase activity is 2% of wild-type enzyme |
660988 |
| 5.1.3.14 | DELTA697-722 |
epimerase activity is about 70% of wild-type enzyme |
660988 |
| 5.1.3.14 | DELTA717-722 |
epimerase activity is about 95% of wild-type enzyme |
660988 |
| 5.1.3.14 | E117Q |
about 18000 fold decrease in turnover number for UDP-N-acetyl-D-glucosamine, not possible to obtain accurate kinetic constants |
661247 |
| 5.1.3.14 | E122Q |
no conversion of UDP-N-acetyl-D-glucosamine to UDP + N-acetyl-D-mannosamine, acetamidoglucal is released from the active site during catalysis |
-, 661102 |
