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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.84P248L/Q41X the mutations are associated with mandibuloacral dysplasia type B and reduced prelamin A cleavage ability 753395
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.84P248L/W450X the mutations are associated with mandibuloacral dysplasia type B and reduced prelamin A cleavage ability 753395
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.84W340R/L362F the mutations are associated with mandibuloacral dysplasia type B and reduced prelamin A cleavage ability 753395
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.84more Zmste24-deficient mice, Zmpste24 deficiency elicits a stress signaling pathway that is evidenced by a marked upregulation of p53 target genes, accompanied by a senescence phenotype at the cellular level and accelerated ageing at the organismal level 670378
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