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EC Number
Protein Variants
Commentary
Reference
3.4.24.84
W340R
the mutant shows 41.7% of wild type activity
753395
3.4.24.84
W340R/L362F
the mutations are associated with mandibuloacral dysplasia type B and reduced prelamin A cleavage ability
753395
3.4.24.84
W450X
0.3% of wild-type activity
735044
3.4.24.84
Y399C
the mutation is associated with mandibuloacral dysplasia type B and reduced prelamin A cleavage ability(25.8% of wild type activity)
753395
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