EC Number   |
Protein Variants |
Reference |
|---|
   3.2.1.123 | E234Q |
no activity |
680753 |
| 3.2.1.123 | E339S |
no hydrolysis of beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-(alpha-Neu5Ac-(2->3))-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide and beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide |
751102 |
| 3.2.1.123 | E341D |
strongly decreased enzyme activity compared with the wild-type enzyme |
680753 |
| 3.2.1.123 | E341Q |
no activity |
680753 |
| 3.2.1.123 | E351A |
mutant glycosidase with glycosynthase activity |
695545 |
| 3.2.1.123 | E351G |
mutant glycosidase with glycosynthase activity |
695545 |
| 3.2.1.123 | E351M |
mutant glycosidase with no glycosynthase activity |
695545 |
| 3.2.1.123 | E351R |
mutant glycosidase with no glycosynthase activity |
695545 |
| 3.2.1.123 | E351S |
mutant glycosidase with glycosynthase activity, most active enzyme for ganglioside synthesis |
695545 |
| 3.2.1.123 | E351S |
prevents substrate hydrolysis during crystallization |
680770 |
