EC Number |
Protein Variants |
Reference |
---|
2.7.7.39 | D94A |
mutant with high Km value |
645247 |
2.7.7.39 | D94A/H14A |
binding constants for CTP and glycerol 3-phosphate are similar to wild-type enzyme |
645249 |
2.7.7.39 | D94E mutant |
mutant with low kcat value |
645247 |
2.7.7.39 | E115A |
mutant with kinetic constants similar to wild-type enzyme |
645247 |
2.7.7.39 | E39A |
mutant with kinetic constants similar to wild-type enzyme |
645247 |
2.7.7.39 | E67A |
mutant with kinetic constants similar to wild-type enzyme |
645247 |
2.7.7.39 | H14A |
Kd value for binding of a single substrate is similar to those for the wild-type enzyme |
645249 |
2.7.7.39 | H14A |
mutant with low kcat value, dramatic loss of activity |
645247 |
2.7.7.39 | H17A |
initial binding constant is similar to wild-type enzyme |
645249 |
2.7.7.39 | H17A |
mutant with low kcat value, dramatic loss of activity |
645247 |