EC Number |
Protein Variants |
Reference |
---|
2.1.1.170 | more |
a rsmG null mutant is streptomycin-resistant |
721042 |
2.1.1.170 | more |
mutations within the gene gidB confer low-level streptomycin resistance. gidB mutations emerge spontaneously at a high frequency of 0.000001 and, once emerged, result in vigorous emergence of high-level streptomycin-resistant mutants at a frequency more than 2000 times greater than that seen in wild-type strains |
-, 705767 |
2.1.1.170 | N39A |
inactive |
733472 |
2.1.1.170 | P79A |
site-directed mutagenesis of the S-adenosyl-L-methionine-binding residue, the mutant is streptomycin-resistant and shows reduced activity compared to the wild-type enzyme |
721042 |
2.1.1.170 | R123A |
site-directed mutagenesis of the RNA-binding residue, the mutant is streptomycin-sensitive, but shows reduced activity compared to the wild-type enzyme |
721042 |
2.1.1.170 | R139A |
site-directed mutagenesis of the catalytic residue, the mutant is streptomycin-resistant and catalytically inactive |
721042 |
2.1.1.170 | R139K |
site-directed mutagenesis of the catalytic residue, the mutant is partly streptomycin-resistant and shows reduced activity compared to the wild-type enzyme |
721042 |
2.1.1.170 | R197A |
site-directed mutagenesis of the RNA binding residue, the mutant is streptomycin-resistant and shows reduced activity compared to the wild-type enzyme |
721042 |