EC Number |
Protein Variants |
Reference |
---|
3.4.21.47 | E301A |
mutation in the Bb component decreases sensitivity to DAF to 75% of the wild-type value |
652225 |
3.4.21.47 | E316A |
mutation in the Bb component decreases sensitivity to DAF to 71% of the wild-type value |
652225 |
3.4.21.47 | E379A |
mutation in the Bb component decreases sensitivity to DAF to 52% of the wild-type value, sensitivity to CR1 to 50% of the wild-type value |
652225 |
3.4.21.47 | E434A |
mutation in the Bb component decreases sensitivity to CR1 to 65% of the wild-type value |
652225 |
3.4.21.47 | K265A/K266A |
Mutation in the Bb component decreases sensitivity to DAF to 18% of the wild-type value, sensitivity to CR1 to 18% of the wild-type value and sensitivity to Factor H to 19% of the wild-type value |
652225 |
3.4.21.47 | K294A |
mutation in the Bb component decreases sensitivity to CR1 to 44% of the wild-type value |
652225 |
3.4.21.47 | M341A |
mutation in the Bb component decreases sensitivity to Factor H to 75% of the wild-type value |
652225 |
3.4.21.47 | N260D |
mutation in the Bb component decreases sensitivity to DAF to 32% of the wild-type value, sensitivity to CR1 to 31% of the wild-type value and sensitivity to Factor H to 24% of the wild-type value |
652225 |
3.4.21.47 | Q335A |
mutation in the Bb component decreases sensitivity to DAF to 20% of the wild-type value |
652225 |
3.4.21.47 | S339A |
mutation in the Bb component decreases sensitivity to DAF to 32% of the wild-type value, sensitivity to CR1 to 50% of the wild-type value |
652225 |