EC Number   |
Protein Variants   |
Reference   |
|---|
 2.1.1.170 | more |
a rsmG null mutant is streptomycin-resistant |
721042 |
 2.1.1.170 | P79A |
site-directed mutagenesis of the S-adenosyl-L-methionine-binding residue, the mutant is streptomycin-resistant and shows reduced activity compared to the wild-type enzyme |
721042 |
 2.1.1.170 | R123A |
site-directed mutagenesis of the RNA-binding residue, the mutant is streptomycin-sensitive, but shows reduced activity compared to the wild-type enzyme |
721042 |
 2.1.1.170 | R139A |
site-directed mutagenesis of the catalytic residue, the mutant is streptomycin-resistant and catalytically inactive |
721042 |
 2.1.1.170 | R139K |
site-directed mutagenesis of the catalytic residue, the mutant is partly streptomycin-resistant and shows reduced activity compared to the wild-type enzyme |
721042 |
 2.1.1.170 | R197A |
site-directed mutagenesis of the RNA binding residue, the mutant is streptomycin-resistant and shows reduced activity compared to the wild-type enzyme |
721042 |
 2.1.1.170 | G75A |
the mutation directly affects the S-adenosyl-L-methionine binding site, presents an almost 4fold loss of affinity and maintains the enzyme active |
733472 |
 2.1.1.170 | N39A |
inactive |
733472 |
 2.1.1.170 | C172S/A14C |
site-directed mutagenesis |
-, 779252 |