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<< < Results 21 - 30 of 31 > >>
EC Number
Amino acid exchange
Commentary
Reference
N67A
drastically reduced activiy
P131A
decrease in activtiy against fumarate
P56A
drastically reduced activiy
Q7L
single nucleotide polymorphism due to missense polymorphism 19C>A, leading to amino acid substitution in the cationic N-terminal region of the polypeptide
R265A
2fold increase in KM-value of CoQD, 15% increase in KM-value of L-dihydroorotate
R50E
little changes in activity
R57A
increase in activity
S129A
decrease in activtiy against fumarate
S175A
-
S175A
low activity with dihydroorotate, increasing activity above pH 8.0 with dihydrooxonate
<< < Results 21 - 30 of 31 > >>