EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    6.3.2.10 | Acute Kidney Injury |
27102410 |
Upregulation of MuRF1 and MAFbx participates to muscle wasting upon gentamicin-induced acute kidney injury. |
unassigned |
0 |
| 6.3.2.10 | Acute Lung Injury |
22312013 |
A Critical Role for Muscle Ring Finger-1 in Acute Lung Injury-Associated Skeletal Muscle Wasting. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
1
4
0 |
| 6.3.2.10 | Arthritis |
16030067 |
Ghrelin receptor agonist GHRP-2 prevents arthritis-induced increase in E3 ubiquitin-ligating enzymes MuRF1 and MAFbx gene expression in skeletal muscle. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 6.3.2.10 | Arthritis |
17284570 |
Experimental arthritis inhibits the insulin-like growth factor-I axis and induces muscle wasting through cyclooxygenase-2 activation. |
ongoing research
therapeutic application
unassigned |
3
4
0 |
| 6.3.2.10 | Arthritis |
19741054 |
Eicosapentaenoic acid attenuates arthritis-induced muscle wasting acting on atrogin-1 and on myogenic regulatory factors. |
therapeutic application
unassigned |
4
0 |
| 6.3.2.10 | Arthritis |
28614768 |
Melanocortin-4 receptor agonist (RO27-3225) ameliorates soleus but not gastrocnemius atrophy in arthritic rats. |
unassigned |
0 |
| 6.3.2.10 | Bone Resorption |
21866567 |
MURF1 deficiency suppresses unloading-induced effects on osteoblasts and osteoclasts to lead to bone loss. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
1
0 |
| 6.3.2.10 | Cardiomegaly |
15596539 |
Muscle ring finger protein-1 inhibits PKC{epsilon} activation and prevents cardiomyocyte hypertrophy. |
causal interaction
therapeutic application
unassigned |
4
3
0 |
| 6.3.2.10 | Cardiomegaly |
16949602 |
Into the heart: The emerging role of the ubiquitin-proteasome system. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 6.3.2.10 | Cardiomegaly |
17272810 |
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
