EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
5.6.1.4 | Bardet-Biedl Syndrome |
9782090 |
Cloning of a novel C-terminal kinesin (KIFC3) that maps to human chromosome 16q13-q21 and thus is a candidate gene for Bardet-Biedl syndrome. |
causal interaction unassigned |
1 0 |
5.6.1.4 | Breast Neoplasms |
19789344 |
Overexpression of kinesins mediates docetaxel resistance in breast cancer cells. |
ongoing research unassigned |
3 0 |
5.6.1.4 | Breast Neoplasms |
25348260 |
Kinesin-14 and kinesin-5 antagonistically regulate microtubule nucleation by ?-TuRC in yeast and human cells. |
therapeutic application unassigned |
1 0 |
5.6.1.4 | Carcinoma, Hepatocellular |
31340839 |
KIFC1 is activated by TCF-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity. |
causal interaction diagnostic usage ongoing research unassigned |
1 1 4 0 |
5.6.1.4 | Influenza, Human |
11581287 |
KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes. |
causal interaction therapeutic application unassigned |
1 1 0 |
5.6.1.4 | Neoplasms |
23895133 |
Discovery and Mechanistic Study of a Small Molecule Inhibitor for Motor Protein KIFC1. |
causal interaction diagnostic usage therapeutic application unassigned |
3 1 3 0 |
5.6.1.4 | Neoplasms |
25458601 |
Discovery of potent KIFC1 inhibitors using a method of integrated high-throughput synthesis and screening. |
causal interaction therapeutic application unassigned |
1 4 0 |
5.6.1.4 | Neoplasms |
26117688 |
The Aspergillus nidulans bimC4 mutation provides an excellent tool for identification of kinesin-14 inhibitors. |
causal interaction therapeutic application unassigned |
1 1 0 |
5.6.1.4 | Neoplasms |
26992853 |
A centrosome clustering protein, KIFC1, predicts aggressive disease course in serous ovarian adenocarcinomas. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 3 3 |
5.6.1.4 | Neoplasms |
29123223 |
Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein. |
causal interaction unassigned |
1 0 |