EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
5.1.1.4 | Brucellosis |
24508400 |
Brucella alters the immune response in a prpA-dependent manner. |
causal interaction unassigned |
3 0 |
5.1.1.4 | Brucellosis |
29929362 |
Vaccination of goats with a combination Salmonella vector expressing four Brucella antigens (BLS, PrpA, Omp19, and SOD) confers protection against Brucella abortus infection. |
therapeutic application unassigned |
3 0 |
5.1.1.4 | Chagas Disease |
12735293 |
Biochemical characterization of proline racemases from the human protozoan parasite Trypanosoma cruzi and definition of putative protein signatures. |
therapeutic application unassigned |
4 0 |
5.1.1.4 | Chagas Disease |
17849014 |
Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens. |
therapeutic application unassigned |
2 0 |
5.1.1.4 | Chagas Disease |
23613764 |
Combined approaches for drug design points the way to novel proline racemase inhibitor candidates to fight Chagas' disease. |
therapeutic application unassigned |
4 0 |
5.1.1.4 | Chagas Disease |
25890302 |
Phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. |
unassigned |
0 |
5.1.1.4 | Infections |
16164548 |
Trypanosoma cruzi proline racemases are involved in parasite differentiation and infectivity. |
therapeutic application unassigned |
1 0 |
5.1.1.4 | Infections |
20140365 |
Inhibition of Trypanosoma cruzi proline racemase affects host-parasite interactions and the outcome of in vitro infection. |
causal interaction diagnostic usage ongoing research therapeutic application |
2 3 2 2 |
5.1.1.4 | Infections |
24416292 |
A proline racemase based PCR for identification of Trypanosoma vivax in cattle blood. |
diagnostic usage therapeutic application unassigned |
3 3 0 |
5.1.1.4 | Infections |
24693984 |
The Clostridium difficile proline racemase is not essential for early logarithmic growth and infection. |
causal interaction unassigned |
3 0 |