EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.5.4.10 | Abortion, Spontaneous |
33030400 |
Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence. |
diagnostic usage ongoing research unassigned |
3 3 0 |
3.5.4.10 | Adenocarcinoma |
24500968 |
Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling. |
unassigned |
0 |
3.5.4.10 | Adenocarcinoma |
34007003 |
ITGA2, LAMB3, and LAMC2 may be the potential therapeutic targets in pancreatic ductal adenocarcinoma: an integrated bioinformatics analysis. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 2 1 4 |
3.5.4.10 | Arthritis |
22083543 |
The loss of integrin ?2?1 suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis. |
causal interaction ongoing research unassigned |
1 3 0 |
3.5.4.10 | Asthma |
29769273 |
Genome-Wide Posttranscriptional Dysregulation by MicroRNAs in Human Asthma as Revealed by Frac-seq. |
unassigned |
0 |
3.5.4.10 | Breast Neoplasms |
16317580 |
Integrin alpha-2 and beta-3 gene polymorphisms and breast cancer risk. |
causal interaction diagnostic usage ongoing research unassigned |
4 4 4 0 |
3.5.4.10 | Breast Neoplasms |
26258411 |
Epigenetic silencing of ITGA2 by MiR-373 promotes cell migration in breast cancer. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 4 2 |
3.5.4.10 | Breast Neoplasms |
34179312 |
ITGA2 promotes expression of ACLY and CCND1 in enhancing breast cancer stemness and metastasis. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 4 1 1 |
3.5.4.10 | Carcinogenesis |
31818309 |
Overexpressed ITGA2 promotes malignant tumor aggression by up-regulating PD-L1 expression through the activation of the STAT3 signaling pathway. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 3 4 |
3.5.4.10 | Carcinogenesis |
32112274 |
microRNA-30a arbitrates intestinal-type early gastric carcinogenesis by directly targeting ITGA2. |
ongoing research therapeutic application unassigned |
1 1 0 |