EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.5.3.15 | Acute Kidney Injury |
29021225 |
ATP induces PAD4 in renal proximal tubule cells via P2X7 receptor activation to exacerbate ischemic AKI. |
causal interaction unassigned |
3 0 |
3.5.3.15 | Acute Kidney Injury |
29357426 |
Divergent roles for kidney proximal tubule and granulocyte PAD4 in ischemic AKI. |
causal interaction ongoing research unassigned |
1 4 0 |
3.5.3.15 | Acute Kidney Injury |
33295402 |
Evaluation of peptidylarginine deiminase 4 and PADI4 polymorphisms in sepsis-induced acute kidney injury. |
causal interaction diagnostic usage ongoing research unassigned |
3 4 2 0 |
3.5.3.15 | Adenocarcinoma |
19183436 |
Increased PADI4 expression in blood and tissues of patients with malignant tumors. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 4 2 |
3.5.3.15 | Adenocarcinoma |
20827398 |
Expression of peptidylarginine deiminase type 4 in ovarian tumors. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 4 4 |
3.5.3.15 | Adenocarcinoma |
21698003 |
Investigating the pathogenic role of PADI4 in oesophageal cancer. |
causal interaction diagnostic usage ongoing research unassigned |
1 3 3 0 |
3.5.3.15 | Adenocarcinoma |
31428515 |
DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth. |
causal interaction therapeutic application unassigned |
4 4 0 |
3.5.3.15 | Adenocarcinoma |
32629995 |
Putative Roles for Peptidylarginine Deiminases in COVID-19. |
causal interaction diagnostic usage ongoing research unassigned |
4 3 2 0 |
3.5.3.15 | Adenocarcinoma |
34295566 |
PADI1 contributes to EMT in PAAD by activating the ERK1/2-p38 signaling pathway. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 2 3 3 |
3.5.3.15 | Adenocarcinoma of Lung |
19183436 |
Increased PADI4 expression in blood and tissues of patients with malignant tumors. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 4 2 |