EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.24.63 | Acquired Immunodeficiency Syndrome |
12749695 |
Aspartic peptidase inhibitors: implications in drug development. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.4.24.63 | Acquired Immunodeficiency Syndrome |
17908045 |
Memapsin 2 (Beta-Secretase) Inhibitor Drug, between Fantasy and Reality. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.4.24.63 | Acquired Immunodeficiency Syndrome |
18763714 |
Design of potent aspartic protease inhibitors to treat various diseases. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.4.24.63 | Alzheimer Disease |
7489411 |
The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway. |
causal interaction
unassigned |
3
0 |
| 3.4.24.63 | Alzheimer Disease |
7970175 |
Reversal of the Swedish familial Alzheimer's disease mutant phenotype in cultured cells treated with phorbol 12,13-dibutyrate. |
causal interaction
therapeutic application
unassigned |
4
2
0 |
| 3.4.24.63 | Alzheimer Disease |
8632167 |
Evaluation of cathepsins D and G and EC 3.4.24.15 as candidate beta-secretase proteases using peptide and amyloid precursor protein substrates. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.4.24.63 | Alzheimer Disease |
8830855 |
Human brain beta-secretase contains heparan sulfate glycoconjugates. |
ongoing research
unassigned |
2
0 |
| 3.4.24.63 | Alzheimer Disease |
8863493 |
Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain. |
unassigned |
0 |
| 3.4.24.63 | Alzheimer Disease |
9593752 |
Regulation of amyloid precursor protein secretion by glutamate receptors in human Ntera 2 neurons. |
causal interaction
unassigned |
3
0 |
| 3.4.24.63 | Alzheimer Disease |
10405162 |
A novel substrate for analyzing Alzheimer's disease gamma-secretase. |
therapeutic application
unassigned |
3
0 |
