EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.23.46 | Abscess |
33171462 |
Hidradenitis Suppurativa: Proposal of Classification in Two Endotypes with Two-Step Cluster Analysis. |
diagnostic usage
unassigned |
1
0 |
| 3.4.23.46 | Acute Kidney Injury |
28971991 |
Targeted gamma-secretase inhibition of Notch signaling activation in acute renal injury. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.4.23.46 | Acute Lung Injury |
29227981 |
Gamma-Secretase Inhibitors Attenuate Neurotrauma and Neurogenic Acute Lung Injury in Rats by Rescuing the Accumulation of Hypertrophic Microglia. |
causal interaction
therapeutic application
unassigned |
2
2
0 |
| 3.4.23.46 | Adenocarcinoma |
19208345 |
Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 3.4.23.46 | Adenocarcinoma |
19405120 |
Essential role of Notch signaling in apoptosis of human pancreatic tumoral cells mediated by exosomal nanoparticles. |
causal interaction
unassigned |
3
0 |
| 3.4.23.46 | Adenocarcinoma |
19789031 |
Pathogenesis of Barrett's esophagus: bile acids inhibit the Notch signaling pathway with induction of CDX2 gene expression in human esophageal cells. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
3
1
0 |
| 3.4.23.46 | Adenocarcinoma |
21187481 |
Gamma-secretase complexes regulate the responses of human pancreatic ductal adenocarcinoma cells to taxanes. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 3.4.23.46 | Adenocarcinoma of Lung |
23444212 |
Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 3.4.23.46 | Albuminuria |
19293596 |
The pathogenic role of notch activation in podocytes. |
ongoing research
unassigned |
1
0 |
| 3.4.23.46 | Alzheimer Disease |
7550356 |
The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Alzheimer's Disease Collaborative Group. |
causal interaction
unassigned |
3
0 |
