EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.69 | Acquired Immunodeficiency Syndrome |
32924827 |
Potential protease inhibitors and their combinations to block SARS-CoV-2. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.4.22.69 | Atherosclerosis |
3143327 |
[Protease inhibitors and ectasia in coronary atherosclerosis] |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
2
4
0 |
| 3.4.22.69 | Atherosclerosis |
25016275 |
The clinical research for Ganoderan's effect on preventing and treating cerebral arteriosclerosis through inhibiting NADPH oxidizing enzyme expression. |
causal interaction
unassigned |
4
0 |
| 3.4.22.69 | Bronchitis |
17183167 |
Preliminary crystallographic analysis of avian infectious bronchitis virus main protease. |
unassigned |
0 |
| 3.4.22.69 | Colonic Neoplasms |
31694340 |
ADAM17 Activity and IL-6 Trans-Signaling in Inflammation and Cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
4 |
| 3.4.22.69 | Communicable Diseases |
33415017 |
Tannic acid suppresses SARS-CoV-2 as a dual inhibitor of the viral main protease and the cellular TMPRSS2 protease. |
causal interaction
therapeutic application
unassigned |
4
3
0 |
| 3.4.22.69 | Coronary Disease |
3143327 |
[Protease inhibitors and ectasia in coronary atherosclerosis] |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
2
4
0 |
| 3.4.22.69 | Coronavirus Infections |
16216498 |
Screening of electrophilic compounds yields an aziridinyl peptide as new active-site directed SARS-CoV main protease inhibitor. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 3.4.22.69 | Coronavirus Infections |
16250642 |
A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 3.4.22.69 | Coronavirus Infections |
25945576 |
Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity. |
unassigned |
0 |
