EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.4.22.61 | Acantholysis |
16014554 |
The interaction of pemphigus autoimmunoglobulins with epidermal cells: activation of the fas apoptotic pathway and the use of caspase activity for pathogenicity tests of pemphigus patients. |
unassigned |
0 |
3.4.22.61 | Acquired Immunodeficiency Syndrome |
11000244 |
Human immunodeficiency virus type 1 Vpr induces apoptosis in human neuronal cells. |
causal interaction therapeutic application unassigned |
4 2 0 |
3.4.22.61 | Acquired Immunodeficiency Syndrome |
11861282 |
Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3. |
causal interaction diagnostic usage therapeutic application unassigned |
4 1 1 0 |
3.4.22.61 | Acute Kidney Injury |
30876938 |
TLR3 is involved in paraquat-induced acute renal injury. |
causal interaction unassigned |
3 0 |
3.4.22.61 | Adenocarcinoma |
10568827 |
Apoptosis of colorectal adenocarcinoma induced by 5-FU and/or IFN-gamma through caspase 3 and caspase 8. |
therapeutic application unassigned |
2 0 |
3.4.22.61 | Adenocarcinoma |
11497260 |
Irofulven (6-hydroxymethylacylfulvene, MGI 114) induces caspase 8 and 9-mediated apoptosis in human pancreatic adenocarcinoma cells. |
ongoing research unassigned |
1 0 |
3.4.22.61 | Adenocarcinoma |
12067831 |
In vivo and in vitro activation of caspase-8 and -3 associated with Helicobacter pylori infection. |
causal interaction diagnostic usage ongoing research unassigned |
4 3 4 0 |
3.4.22.61 | Adenocarcinoma |
14636156 |
Overexpression of cellular FLICE-inhibitory protein (FLIP) in gastric adenocarcinoma. |
diagnostic usage ongoing research unassigned |
3 3 0 |
3.4.22.61 | Adenocarcinoma |
15025952 |
[Expression of cellular FLICE inhibitory protein (cFLIP) in endometrial adenocarcinoma] |
causal interaction therapeutic application unassigned |
4 1 0 |
3.4.22.61 | Adenocarcinoma |
15087380 |
Caspase-8-dependent HER-2 cleavage in response to tumor necrosis factor alpha stimulation is counteracted by nuclear factor kappaB through c-FLIP-L expression. |
causal interaction therapeutic application unassigned |
4 1 0 |