EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.58 | Arthritis, Rheumatoid |
29158166 |
The association between caspase-5 gene polymorphisms and rheumatoid arthritis in a Chinese population. |
causal interaction
unassigned |
1
0 |
| 3.4.22.58 | Asthma |
24136334 |
Elevated expression of the NLRP3 inflammasome in neutrophilic asthma. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
1
1
0 |
| 3.4.22.58 | Breast Neoplasms |
18430458 |
Mutational analysis of caspase 1, 4, and 5 genes in common human cancers. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 3.4.22.58 | Carcinogenesis |
18430458 |
Mutational analysis of caspase 1, 4, and 5 genes in common human cancers. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 3.4.22.58 | Carcinoma |
17676485 |
TGF-betaRII, BAX, IGFIIR, caspase-5, hMSH3 and hMSH6 alterations are not associated with microsatellite instability or p53 mutations in invasive urothelial carcinoma of the urinary bladder. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
3
3
0 |
| 3.4.22.58 | Carcinoma |
18430458 |
Mutational analysis of caspase 1, 4, and 5 genes in common human cancers. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 3.4.22.58 | Cholera |
26158519 |
Single-cell imaging of inflammatory caspase dimerization reveals differential recruitment to inflammasomes. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 3.4.22.58 | Colorectal Neoplasms |
15088110 |
BAX and caspase-5 frameshift mutations and spontaneous apoptosis in colorectal cancer with microsatellite instability. |
causal interaction
diagnostic usage
unassigned |
1
1
0 |
| 3.4.22.58 | Colorectal Neoplasms |
18430458 |
Mutational analysis of caspase 1, 4, and 5 genes in common human cancers. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 3.4.22.58 | Cowpox |
16465268 |
Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases. |
therapeutic application
unassigned |
1
0 |
