EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.4.22.48 | Bone Resorption |
27714883 |
Characteristics of C-terminal, ?-amyloid peptide binding fragment of neuroprotective protease inhibitor, cystatin C. |
causal interaction therapeutic application unassigned |
4 1 0 |
3.4.22.48 | Dermatitis, Atopic |
28821865 |
Identification of bacterial biofilm and the Staphylococcus aureus derived protease, staphopain, on the skin surface of patients with atopic dermatitis. |
diagnostic usage ongoing research therapeutic application unassigned |
3 2 1 0 |
3.4.22.48 | Infections |
10085018 |
Extracellular cysteine protease produced by Streptococcus pyogenes participates in the pathogenesis of invasive skin infection and dissemination in mice. |
causal interaction ongoing research therapeutic application unassigned |
2 4 1 0 |
3.4.22.48 | Infections |
10816533 |
Replacement of histidine 340 with alanine inactivates the group A Streptococcus extracellular cysteine protease virulence factor. |
causal interaction unassigned |
3 0 |
3.4.22.48 | Infections |
22040048 |
An amino-terminal signal peptide of Vfr protein negatively influences RopB-dependent SpeB expression and attenuates virulence in Streptococcus pyogenes. |
causal interaction unassigned |
3 0 |
3.4.22.48 | Infections |
34473800 |
Intracellular Staphylococcus aureus employs the cysteine protease staphopain A to induce host cell death in epithelial cells. |
causal interaction diagnostic usage ongoing research unassigned |
2 3 3 0 |
3.4.22.48 | Keratitis |
32147399 |
The role of staphopain a in Staphylococcus aureus keratitis. |
causal interaction ongoing research therapeutic application unassigned |
4 4 1 0 |
3.4.22.48 | Lung Neoplasms |
9360839 |
Enriched SSCP: a highly sensitive method for the detection of unknown mutations. Application to the molecular diagnosis of lung cancer in sputum samples. |
diagnostic usage unassigned |
4 0 |
3.4.22.48 | Neoplasms |
9360839 |
Enriched SSCP: a highly sensitive method for the detection of unknown mutations. Application to the molecular diagnosis of lung cancer in sputum samples. |
diagnostic usage unassigned |
4 0 |
3.4.22.48 | Neoplasms |
22751990 |
Extracellular protease imaging for cell mass tracking of xenografted human malignant pleural mesothelioma. |
causal interaction diagnostic usage ongoing research therapeutic application |
2 1 4 1 |