EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.B6 | Adenocarcinoma |
11173941 |
Blood-borne RT-PCR assay for prostasin- specific transcripts to identify circulating prostate cells in cancer patients. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
1
4
1
0 |
| 3.4.21.B6 | Adenocarcinoma |
12441343 |
Structure and activity of human pancreasin, a novel tryptic serine peptidase expressed primarily by the pancreas. |
causal interaction
unassigned |
3
0 |
| 3.4.21.B6 | Adenocarcinoma |
23707658 |
Axl and prostasin are biomarkers for prognosis of ovarian adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 3.4.21.B6 | Adenocarcinoma |
27050145 |
Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
3
3 |
| 3.4.21.B6 | Adenocarcinoma |
34089062 |
Targeted HAI-2 deletion causes excessive proteolysis with prolonged active prostasin and depletion of HAI-1 monomer in intestinal but not epidermal epithelial cells. |
ongoing research
unassigned |
4
0 |
| 3.4.21.B6 | Adenoma |
27050145 |
Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
3
3 |
| 3.4.21.B6 | Albuminuria |
28233126 |
Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 3.4.21.B6 | Breast Neoplasms |
11774283 |
Prostasin serine protease inhibits breast cancer invasiveness and is transcriptionally regulated by promoter DNA methylation. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 3.4.21.B6 | Breast Neoplasms |
16822939 |
Prostasin regulates epithelial monolayer function: cell-specific Gpld1-mediated secretion and functional role for GPI anchor. |
causal interaction
diagnostic usage
unassigned |
3
3
0 |
| 3.4.21.B6 | Breast Neoplasms |
21678412 |
Strong expression association between matriptase and its substrate prostasin in breast cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
4
4
0 |
