EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.4.21.B26 | Adenocarcinoma |
19737405 |
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model. |
causal interaction ongoing research therapeutic application unassigned |
4 4 1 0 |
3.4.21.B26 | Anorectal Malformations |
21480163 |
PCSK5 and GDF11 Expression in the Hindgut Region of Mouse Embryos with Anorectal Malformations. |
unassigned |
0 |
3.4.21.B26 | Anorectal Malformations |
23127126 |
Anorectal atresia and variants at predicted regulatory sites in candidate genes. |
diagnostic usage unassigned |
2 0 |
3.4.21.B26 | Anorectal Malformations |
28446132 |
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development. |
unassigned |
0 |
3.4.21.B26 | Anorectal Malformations |
28975535 |
Spatiotemporal expression of proprotein convertase subtilisin/kexin type 5 in the development of anorectal malformations in fetal rats. |
ongoing research unassigned |
4 0 |
3.4.21.B26 | Anus, Imperforate |
28446132 |
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development. |
unassigned |
0 |
3.4.21.B26 | Atherosclerosis |
21889147 |
Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL. |
causal interaction unassigned |
3 0 |
3.4.21.B26 | Breast Neoplasms |
29161592 |
Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. |
therapeutic application unassigned |
1 0 |
3.4.21.B26 | Carcinogenesis |
19737405 |
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model. |
causal interaction ongoing research therapeutic application unassigned |
4 4 1 0 |
3.4.21.B26 | Cardiovascular Diseases |
20031622 |
Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels. |
causal interaction diagnostic usage unassigned |
3 3 0 |