EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.112 | Alkalosis |
1812375 |
Alkalosis monitored by 31P NMR in a human glioma cell line exposed to the anti-tumor drug 1,3-bis(2-chloroethyl)-1-nitrosourea. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 3.4.21.112 | Carcinogenesis |
23884247 |
Inhibition of the Prohormone Convertase Subtilisin-Kexin Isoenzyme-1 Induces Apoptosis in Human Melanoma Cells. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
3 |
| 3.4.21.112 | Carcinoma |
34285190 |
SREBP1 site 1 protease inhibitor PF-429242 suppresses renal cell carcinoma cell growth. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
3
2
0 |
| 3.4.21.112 | Carcinoma, Hepatocellular |
22241994 |
Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
4
0 |
| 3.4.21.112 | Carcinoma, Hepatocellular |
27833850 |
Baicalin promoted site-2 protease and not site-1 protease in endoplasmic reticulum stress-induced apoptosis of human hepatocellular carcinoma cells. |
ongoing research
unassigned |
3
0 |
| 3.4.21.112 | Carcinoma, Hepatocellular |
28339489 |
Human Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P) regulates cytoplasmic lipid droplet abundance: A potential target for indirect-acting anti-dengue virus agents. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
4
0 |
| 3.4.21.112 | Carcinoma, Renal Cell |
34285190 |
SREBP1 site 1 protease inhibitor PF-429242 suppresses renal cell carcinoma cell growth. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
3
2
0 |
| 3.4.21.112 | Choriocarcinoma |
34423782 |
The (pro)renin receptor and soluble (pro)renin receptor in choriocarcinoma. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 3.4.21.112 | Congenital Abnormalities |
32857899 |
Patient with an autosomal-recessive MBTPS1-linked phenotype and clinical features of Silver-Russell syndrome. |
unassigned |
0 |
| 3.4.21.112 | Dengue |
26875984 |
Suppressive Effects of the Site 1 Protease (S1P) Inhibitor, PF-429242, on Dengue Virus Propagation. |
ongoing research
unassigned |
3
0 |
