EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.4.21.107 | Acidosis, Lactic |
32196841 |
Monogenic cerebral small-vessel diseases: diagnosis and therapy. Consensus recommendations of the European Academy of Neurology. |
unassigned |
0 |
3.4.21.107 | Adenocarcinoma |
29168038 |
Ovarian serous carcinomas acquire cisplatin resistance and increased invasion through downregulation of the high-temperature-required protein A2 (HtrA2), following repeated treatment with cisplatin. |
causal interaction diagnostic usage ongoing research unassigned |
4 4 4 0 |
3.4.21.107 | Adenocarcinoma of Lung |
24356998 |
HtrA1 Downregulation Induces Cisplatin Resistance in Lung Adenocarcinoma by Promoting Cancer Stem Cell-Like Properties. |
diagnostic usage ongoing research therapeutic application unassigned |
2 3 2 0 |
3.4.21.107 | Adenocarcinoma of Lung |
31180543 |
Long intergenic non?coding RNA 00467 promotes lung adenocarcinoma proliferation, migration and invasion by binding with EZH2 and repressing HTRA3 expression. |
causal interaction unassigned |
2 0 |
3.4.21.107 | Adenocarcinoma, Follicular |
22923201 |
Changes in expression of human serine protease HtrA1, HtrA2 and HtrA3 genes in benign and malignant thyroid tumors. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 2 4 4 |
3.4.21.107 | Adenoma |
28586045 |
Low HtrA1 expression in patients with long?standing ulcerative colitis and colorectal cancer. |
causal interaction diagnostic usage ongoing research unassigned |
1 4 3 0 |
3.4.21.107 | Aggressive Periodontitis |
24979214 |
The novel role of HtrA1 in gingivitis, chronic and aggressive periodontitis. |
causal interaction diagnostic usage ongoing research unassigned |
3 3 4 0 |
3.4.21.107 | Alopecia |
21215656 |
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL): from discovery to gene identification. |
causal interaction therapeutic application unassigned |
3 2 0 |
3.4.21.107 | Alopecia |
21301034 |
[Carasil]. |
causal interaction therapeutic application unassigned |
3 4 0 |
3.4.21.107 | Alopecia |
21482952 |
A novel mutation in the HTRA1 gene causes CARASIL without alopecia. |
causal interaction unassigned |
3 0 |