EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.17.16 | Angioedema |
31984307 |
Lisinopril-Induced Angioedema in a Patient with Plasma Prekallikrein Deficiency. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.4.17.16 | Breast Neoplasms |
21087932 |
Prolylcarboxypeptidase regulates proliferation, autophagy, and resistance to 4-hydroxytamoxifen-induced cytotoxicity in estrogen receptor-positive breast cancer cells. |
therapeutic application
unassigned |
2
0 |
| 3.4.17.16 | Breast Neoplasms |
24936056 |
The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT. |
causal interaction
unassigned |
3
0 |
| 3.4.17.16 | Diabetes Mellitus |
22539806 |
Plasma prolylcarboxypeptidase (angiotensinase C) is increased in obesity and diabetes mellitus and related to cardiovascular dysfunction. |
causal interaction
unassigned |
3
0 |
| 3.4.17.16 | Essential Hypertension |
22679278 |
Association of polymorphisms in prolylcarboxypeptidase and chymase genes with essential hypertension in the Chinese Han population. |
causal interaction
unassigned |
3
0 |
| 3.4.17.16 | Essential Hypertension |
32448049 |
Genetic association study of prolylcarboxypeptidase polymorphisms with susceptibility to essential hypertension in the Yi minority of China: A case-control study based on an isolated population. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
2
1
0 |
| 3.4.17.16 | Hypertension |
16681991 |
Prolylcarboxypeptidase gene, chronic hypertension, and risk of preeclampsia. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
2
3
1 |
| 3.4.17.16 | Hypertension |
20516604 |
Expression, purification and crystallization of human prolylcarboxypeptidase. |
causal interaction
unassigned |
3
0 |
| 3.4.17.16 | Hypertension |
21297000 |
Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis. |
causal interaction
ongoing research
unassigned |
4
1
0 |
| 3.4.17.16 | Hypertension |
23744584 |
Prolylcarboxypeptidase promotes angiogenesis and vascular repair. |
causal interaction
unassigned |
3
0 |
