EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.2.2.31 | Carcinogenesis |
25029543 |
Cellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cells. |
unassigned |
0 |
3.2.2.31 | Colonic Neoplasms |
22684101 |
DNA repair is indispensable for survival after acute inflammation. |
ongoing research therapeutic application unassigned |
3 1 0 |
3.2.2.31 | Colorectal Neoplasms |
12628248 |
Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E.coli enzymes. |
diagnostic usage unassigned |
1 0 |
3.2.2.31 | Colorectal Neoplasms |
15661655 |
Insight into the functional consequences of hMYH variants associated with colorectal cancer: distinct differences in the adenine glycosylase activity and the response to AP endonucleases of Y150C and G365D murine MYH. |
ongoing research unassigned |
2 0 |
3.2.2.31 | Neoplasms |
20848659 |
Adenine DNA glycosylase activity of 14 Human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer. |
causal interaction diagnostic usage unassigned |
1 2 0 |
3.2.2.31 | Neoplasms |
25310643 |
MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death. |
causal interaction ongoing research therapeutic application unassigned |
3 2 3 0 |
3.2.2.31 | Neoplasms |
25706342 |
MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death. |
ongoing research unassigned |
2 0 |
3.2.2.31 | Neoplasms |
34142156 |
Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. |
therapeutic application unassigned |
1 0 |