EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.6.14 | arylsulfatase (type i) deficiency |
2127527 |
A screening method for mucopolysaccharidoses with increased urinary excretion of sulfated N-acetylhexosamines. |
diagnostic usage
ongoing research
unassigned |
4
4
0 |
| 3.1.6.14 | Carcinoma, Ductal |
18928525 |
Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma. |
causal interaction
diagnostic usage
unassigned |
1
1
0 |
| 3.1.6.14 | Carcinoma, Hepatocellular |
27626699 |
Over expression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo. |
causal interaction
unassigned |
4
0 |
| 3.1.6.14 | Carcinoma, Intraductal, Noninfiltrating |
18928525 |
Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma. |
causal interaction
diagnostic usage
unassigned |
1
1
0 |
| 3.1.6.14 | Liver Neoplasms |
27626699 |
Over expression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo. |
causal interaction
unassigned |
4
0 |
| 3.1.6.14 | Liver Neoplasms |
29275459 |
Sulfatase-1 knockdown promotes in vitro and in vivo aggressive behavior of murine hepatocarcinoma Hca-P cells through up-regulation of mesothelin. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
3 |
| 3.1.6.14 | Lung Neoplasms |
31499680 |
MicroRNA-527 inhibits TGF-?/SMAD induced epithelial-mesenchymal transition via downregulating SULF2 expression in non-small-cell lung cancer. |
unassigned |
0 |
| 3.1.6.14 | Lymphatic Metastasis |
27626699 |
Over expression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo. |
causal interaction
unassigned |
4
0 |
| 3.1.6.14 | Lymphatic Metastasis |
31898662 |
Upregulation of sulfatase-1 decreases metastatic potential of SKOV3 human ovarian cancer cells in vitro and in vivo. |
causal interaction
ongoing research
unassigned |
4
4
0 |
| 3.1.6.14 | Lysosomal Storage Diseases |
15456941 |
Caprine mucopolysaccharidosis IIID: fetal and neonatal brain and liver glycosaminoglycan and morphological perturbations. |
causal interaction
unassigned |
4
0 |
