EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.1.98 | Adenoma |
34079124 |
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
1
3
1 |
| 3.1.1.98 | Alzheimer Disease |
33033363 |
Caffeine inhibits Notum activity by binding at the catalytic pocket. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.1.1.98 | Alzheimer Disease |
34292747 |
Structural Insights into Notum Covalent Inhibition. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.1.1.98 | Carcinoma |
34402722 |
Notum palmitoleoyl-protein carboxylesterase regulates Fas cell surface death receptor-mediated apoptosis via the Wnt signaling pathway in colon adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
3 |
| 3.1.1.98 | Carcinoma, Hepatocellular |
18429952 |
Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 3.1.1.98 | Colonic Neoplasms |
34402722 |
Notum palmitoleoyl-protein carboxylesterase regulates Fas cell surface death receptor-mediated apoptosis via the Wnt signaling pathway in colon adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
3 |
| 3.1.1.98 | Colorectal Neoplasms |
26517809 |
Novel insights into Notum and glypicans regulation in colorectal cancer. |
ongoing research
unassigned |
1
0 |
| 3.1.1.98 | Colorectal Neoplasms |
30343282 |
NOTUM Is Involved in the Progression of Colorectal Cancer. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 3.1.1.98 | Colorectal Neoplasms |
34079124 |
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
1
3
1 |
| 3.1.1.98 | Dentin Dysplasia |
26926082 |
Dentin Dysplasia in Notum Knockout Mice. |
ongoing research
therapeutic application
unassigned |
4
2
0 |
