EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
2.7.7.14 | Atherosclerosis |
22820672 |
Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2. |
causal interaction ongoing research therapeutic application unassigned |
3 4 4 0 |
2.7.7.14 | Breast Neoplasms |
16023412 |
Characterization of transcription factors and cis-acting elements that regulate human CTP: phosphoethanolamine cytidylyltransferase (Pcyt2). |
diagnostic usage ongoing research unassigned |
3 4 0 |
2.7.7.14 | Breast Neoplasms |
22339418 |
Breast cancer cells adapt to metabolic stress by increasing ethanolamine phospholipid synthesis and CTP:ethanolaminephosphate cytidylyltransferase-Pcyt2 activity. |
causal interaction therapeutic application unassigned |
1 1 0 |
2.7.7.14 | Breast Neoplasms |
22820672 |
Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2. |
causal interaction ongoing research therapeutic application unassigned |
3 4 4 0 |
2.7.7.14 | Breast Neoplasms |
31577958 |
Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2. |
causal interaction diagnostic usage ongoing research unassigned |
3 3 3 0 |
2.7.7.14 | Dwarfism |
17189343 |
Defects in CTP:PHOSPHORYLETHANOLAMINE CYTIDYLYLTRANSFERASE affect embryonic and postembryonic development in Arabidopsis. |
unassigned |
0 |
2.7.7.14 | Epilepsy |
31637422 |
Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia. |
causal interaction therapeutic application unassigned |
3 3 0 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase deficiency |
19625253 |
The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice. |
causal interaction unassigned |
3 0 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase deficiency |
22764088 |
Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 3 4 2 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase deficiency |
26242921 |
Choline supplementation restores substrate balance and alleviates complications of Pcyt2 deficiency. |
causal interaction unassigned |
2 0 |