EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.5.1.75 | Adenocarcinoma of Lung |
17145094 |
Ethnic differences in frequencies of gene polymorphisms in the MYCL1 region and modulation of lung cancer patients' survival. |
causal interaction
diagnostic usage
unassigned |
2
3
0 |
| 2.5.1.75 | African Swine Fever |
10364254 |
The African swine fever virus prenyltransferase is an integral membrane trans-geranylgeranyl-diphosphate synthase. |
unassigned |
0 |
| 2.5.1.75 | Arthritis, Rheumatoid |
17763406 |
Protein isoprenylation regulates secretion of matrix metalloproteinase 1 from rheumatoid synovial fibroblasts: effects of statins and farnesyl and geranylgeranyl transferase inhibitors. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 2.5.1.75 | Blindness |
25051182 |
Structure of a membrane-embedded prenyltransferase homologous to UBIAD1. |
causal interaction
unassigned |
4
0 |
| 2.5.1.75 | Cardiomegaly |
30483777 |
UBIAD1 expression is associated with cardiac hypertrophy in spontaneously hypertensive rats. |
ongoing research
unassigned |
2
0 |
| 2.5.1.75 | Cardiovascular Diseases |
28901410 |
Depletion of ubiA prenyltransferase domain containing 1 expression promotes angiotensin II?induced hypertrophic response in AC16 human myocardial cells via modulating the expression levels of coenzyme Q10 and endothelial nitric oxide synthase. |
unassigned |
0 |
| 2.5.1.75 | Choroideremia |
30936521 |
Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics. |
therapeutic application
unassigned |
1
0 |
| 2.5.1.75 | Corneal Dystrophies, Hereditary |
17668063 |
Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 2.5.1.75 | Corneal Dystrophies, Hereditary |
19394700 |
In Vivo Laser Confocal Microscopy Findings and Mutational Analysis for Schnyder's Crystalline Corneal Dystrophy. |
ongoing research
unassigned |
1
0 |
| 2.5.1.75 | Corneal Dystrophies, Hereditary |
20505825 |
UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy. |
causal interaction
unassigned |
1
0 |
