EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.5.1.22 | Breast Neoplasms |
7850811 |
Antiproliferative effect of spermine depletion by N-cyclohexyl-1,3-diaminopropane in human breast cancer cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
4
0 |
| 2.5.1.22 | Breast Neoplasms |
31503278 |
Association between plasma diacetylspermine and tumor spermine synthase with outcome in triple negative breast cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
4
2
0 |
| 2.5.1.22 | Carcinogenesis |
22258329 |
Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
4
2 |
| 2.5.1.22 | Carcinoma |
15377278 |
Independent roles of eIF5A and polyamines in cell proliferation. |
ongoing research
therapeutic application
unassigned |
3
4
0 |
| 2.5.1.22 | Carcinoma, Hepatocellular |
2843368 |
Fluorinated analogues of spermidine as substrates of spermine synthase. |
therapeutic application
unassigned |
1
0 |
| 2.5.1.22 | Carcinoma, Hepatocellular |
2917558 |
Inhibition of mammalian spermine synthase by N-alkylated-1,3-diaminopropane derivatives in vitro and in cultured rat hepatoma cells. |
ongoing research
therapeutic application
unassigned |
4
4
0 |
| 2.5.1.22 | Carcinoma, Hepatocellular |
7608122 |
Specific depletion of spermidine and spermine in HTC cells treated with inhibitors of aminopropyltransferases. |
ongoing research
unassigned |
4
0 |
| 2.5.1.22 | Colorectal Neoplasms |
32591507 |
Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression. |
diagnostic usage
unassigned |
1
0 |
| 2.5.1.22 | Colorectal Neoplasms |
33913723 |
Supramolecular Chemotherapy: Host-Guest Complexes of Heptaplatin-Cucurbit[7]uril toward Colorectal Normal and Tumor Cells. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 2.5.1.22 | Colorectal Neoplasms |
34333979 |
Supramolecular Chemotherapy: Noncovalent Bond Synergy of Cucurbit[7]uril against Human Colorectal Tumor Cells. |
ongoing research
unassigned |
1
0 |
