EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.4.1.102 | Adenocarcinoma |
11280791 |
Clinicopathological significance of core 2 beta1,6-N-acetylglucosaminyltransferase messenger RNA expressed in the pulmonary adenocarcinoma determined by in situ hybridization. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 2.4.1.102 | Adenocarcinoma |
17553459 |
Butyrate induces sLex synthesis by stimulation of selective glycosyltransferase genes. |
ongoing research
unassigned |
3
0 |
| 2.4.1.102 | Adenocarcinoma |
19267921 |
The high affinity selectin glycan ligand C2-O-sLex and mRNA transcripts of the core 2 beta-1,6-N-acetylglucosaminyltransferase (C2GnT1) gene are highly expressed in human colorectal adenocarcinomas. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
4
3
0 |
| 2.4.1.102 | beta-1,3-galactosyl-o-glycosyl-glycoprotein beta-1,6-n-acetylglucosaminyltransferase deficiency |
19057022 |
Core2 1-6-N-glucosaminyltransferase-I is crucial for the formation of atherosclerotic lesions in apolipoprotein E-deficient mice. |
causal interaction
diagnostic usage
unassigned |
3
3
0 |
| 2.4.1.102 | beta-1,3-galactosyl-o-glycosyl-glycoprotein beta-1,6-n-acetylglucosaminyltransferase deficiency |
19349303 |
Glycosyltransferase Function in Core 2-Type Protein O-Glycosylation. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
1
0 |
| 2.4.1.102 | beta-1,3-galactosyl-o-glycosyl-glycoprotein beta-1,6-n-acetylglucosaminyltransferase deficiency |
19372458 |
Core2 1-6-N-Glucosaminyltransferase-I Deficiency Protects Injured Arteries From Neointima Formation in ApoE-Deficient Mice. |
causal interaction
unassigned |
4
0 |
| 2.4.1.102 | beta-1,3-galactosyl-o-glycosyl-glycoprotein beta-1,6-n-acetylglucosaminyltransferase deficiency |
32203062 |
Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
1
0 |
| 2.4.1.102 | Breast Neoplasms |
11118434 |
The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1. |
causal interaction
unassigned |
3
0 |
| 2.4.1.102 | Carcinogenesis |
16464868 |
Co-expression of matriptase and N-acetylglucosaminyltransferase V in thyroid cancer tissues--its possible role in prolonged stability in vivo by aberrant glycosylation. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
2 |
| 2.4.1.102 | Carcinogenesis |
26880801 |
Small-Molecule Inhibition of GCNT3 Disrupts Mucin Biosynthesis and Malignant Cellular Behaviors in Pancreatic Cancer. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
1
0 |
