EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.3.1.297 | Adenocarcinoma |
33183094 |
Ceramide synthases: insights into the expression and prognosis of lung cancer. |
unassigned |
0 |
| 2.3.1.297 | Albuminuria |
21691125 |
Chronic kidney disease: novel insights from genome-wide association studies. |
therapeutic application
unassigned |
1
0 |
| 2.3.1.297 | Albuminuria |
25238615 |
A gene variant in CERS2 is associated with rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND. |
causal interaction
diagnostic usage
unassigned |
4
2
0 |
| 2.3.1.297 | Alzheimer Disease |
27255818 |
Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease. |
causal interaction
unassigned |
2
0 |
| 2.3.1.297 | Asthma |
33800208 |
Ceramide Synthase 2 Null Mice Are Protected from Ovalbumin-Induced Asthma with Higher T Cell Receptor Signal Strength in CD4+ T Cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
3
4
0 |
| 2.3.1.297 | Breast Neoplasms |
19657789 |
Acid ceramidase 1 expression correlates with a better prognosis in ER-positive breast cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 2.3.1.297 | Breast Neoplasms |
19905902 |
Acid ceramidase 1 expression correlates with a better prognosis in ER-positive breast cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 2.3.1.297 | Breast Neoplasms |
19912991 |
Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 2.3.1.297 | Breast Neoplasms |
22230369 |
Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 2.3.1.297 | Breast Neoplasms |
22580606 |
LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
1
3
3
1 |
