EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.1.1.79 | Granuloma |
30308157 |
Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling. |
ongoing research
unassigned |
2
0 |
| 2.1.1.79 | Infections |
15710652 |
Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule. |
causal interaction
unassigned |
2
0 |
| 2.1.1.79 | Infections |
16741578 |
Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis -induced inflammation and virulence. |
unassigned |
0 |
| 2.1.1.79 | Leishmaniasis, Cutaneous |
23251490 |
Functional analysis of Leishmania cyclopropane fatty acid synthetase. |
therapeutic application
unassigned |
1
0 |
| 2.1.1.79 | Starvation |
7007364 |
Augmentation of cyclopropane fatty acid synthesis under stringent control in Escherichia coli. |
causal interaction
unassigned |
4
0 |
| 2.1.1.79 | Tuberculosis |
12502719 |
The mmaA2 gene of Mycobacterium tuberculosis encodes the distal cyclopropane synthase of the alpha-mycolic acid. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 2.1.1.79 | Tuberculosis |
15026045 |
Synthesis and evaluation of analogues of S-adenosyl-L-methionine, as inhibitors of the E. coli cyclopropane fatty acid synthase. |
therapeutic application
unassigned |
4
0 |
| 2.1.1.79 | Tuberculosis |
16216082 |
Escherichia coli cyclopropane fatty acid synthase: is a bound bicarbonate ion the active-site base? |
therapeutic application
unassigned |
1
0 |
| 2.1.1.79 | Tuberculosis |
20472794 |
Redundant function of cmaA2 and mmaA2 in Mycobacterium tuberculosis cis cyclopropanation of oxygenated mycolates. |
therapeutic application
unassigned |
4
0 |
| 2.1.1.79 | Tuberculosis |
24780591 |
Molecular dynamics investigation of the active site dynamics of mycobacterial cyclopropane synthase during various stages of the cyclopropanation process. |
causal interaction
therapeutic application
unassigned |
4
2
0 |
